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Isolated Supraclavicular Lymph Node Metastasis in Primary Breast Carcinoma: A Multimodality Imaging Diagnosis of a Rare Pattern of Spread

Year: 2026

Type: article

Abstract: Breast carcinoma commonly metastasizes to axillary and internal mammary lymph nodes, while isolated supraclavicular lymph node metastasis (ISLM) without axillary involvement is rare. We report a 70-year-old female who presented with a painless left supraclavicular swelling and an unexamined left breast mass. Imaging, including ultrasonography, contrast-enhanced CT, PET/CT and histopathological examination revealed a left breast lesion and ISLM, with no axillary or distant metastases. The patient underwent left mastectomy with sentinel lymph node biopsy, followed by adjuvant chemotherapy, radiotherapy including the supraclavicular region, and endocrine therapy. This case highlights the diagnostic challenge of ISLM, emphasizing the role of multimodal imaging and histopathologic confirmation. Early recognition and aggressive multimodality treatment can achieve locoregional control and favorable outcomes, supporting curative-intent management in selected patients with ISLM.

Source: Saudi Journal of Radiology

DOI: 10.55038/s9se5h92

Authors: Thuraya Aljahwashi, Rusha Sarhan, Anfal Alzillaee, Rabab Badri

Institution: Asir Central Hospital

Language: English

Topic: Breast Lesions and Carcinomas

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7140696708

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