Complete Atelectasis of Left Lung due to Methotrexate-associated Lymphoproliferative Disorder: A Case Report
Year: 2026
Type: article
Study design: Case Report
Abstract: A 59-year-old man who had been treated with methotrexate (MTX) for rheumatoid arthritis was referred to our hospital because of dyspnea. Chest computed tomography revealed a mass obstructing the left main bronchus and complete atelectasis of the left lung. Histopathology of the tumor obtained by trans-bronchial biopsies showed lymphoproliferative disorder (LPD) with positive results for Epstein-Barr virus-encoded small ribonucleic acid in situ hybridization. Withdrawal of MTX resulted in remission of both the tumor and atelectasis, supporting the diagnosis of MTX-associated LPD (MTX-LPD). We herein report a rare case of MTX-LPD with complete atelectasis of a unilateral lung.
Source: Respiratory Endoscopy
Institutions: Aichi Medical University, Aichi Medical University Hospital
Language: English
Subfield: Oncology
Field: Medicine
Domain: Health Sciences
Open Access status: hybrid
OpenAlex ID: W7140761925
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