Work

Persistent luminescence nanoparticles in phototheranostics: Recent progress and translational outlook

Year: 2026

Type: article

Abstract: Phototheranostics has become a precise medicine paradigm by virtue of its spatiotemporal switch characteristic. Thanks to the excitation, energy storage and afterglow emission mechanism and the efficient excitation of broadband light sources, persistent luminescence nanoparticles (PLNPs) effectively overcome the bottlenecks of traditional fluorescent probes, such as background fluorescence, photobleaching and insufficient penetration depth. It has shown unique application prospects in phototheranostics. This review follows a multimodal excitation, afterglow performance and biological application roadmap to systematically introduce the latest progress of PLNPs-based phototheranostics. Besides, the prospects and challenges of its clinical transformation were deeply dissected, with the aim of providing theoretical guidance for PLNPs to move from laboratory innovation to clinical application.

Source: Advanced Sensor and Energy Materials

Authors: Xu Zhao, Li-Xia Yan, Zhu-Ying Yan, Li-Jian Chen, Xiu-Ping Yan

Institutions: Jiangnan University, State Administration for Market Regulation

Language: English

Topic: Luminescence Properties of Advanced Materials

Subfield: Materials Chemistry

Field: Materials Science

Domain: Physical Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $1,600

Funder: National Natural Science Foundation of China