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Large left atrial myxoma with functional mitral stenosis: a case report

Year: 2026

Type: article

Abstract: BACKGROUND: Left atrial myxomas are rare, potentially life-threatening benign cardiac tumors. Early surgical excision is recommended to prevent embolic events, obstruction, and sudden death. A 72-year-old Turkish woman presented with exertional dyspnea and palpitations. Transthoracic echocardiography demonstrated a 4.7 cm × 2.7 cm mobile left atrial mass attached to the interatrial septum and prolapsing into the mitral orifice with a mean transmitral gradient of 9 mmHg and no evidence of embolization. Elective median sternotomy under cardiopulmonary bypass via a right atriotomy-transseptal approach enabled en bloc excision with primary septal closure. Postoperative transesophageal echocardiography confirmed complete resection with preserved mitral valve function, and the mean transmitral gradient fell immediately to ~1.3-1.4 mmHg, indicating prompt hemodynamic normalization. Recovery was uneventful, and the patient was discharged on postoperative day 8. DISCUSSION: This case demonstrates the rapid reversal of myxoma-related functional mitral stenosis following valve-sparing transseptal excision, with immediate normalization of the mean transmitral gradient.

Source: Journal of Medical Case Reports

DOI: 10.1186/s13256-026-05883-6

Authors: Burak Bozkurt, Bingül Dilekçi Şahin, Üzeyir Yılmaz, Güler Gülsen Ersoy

Institutions: Kastamonu Education and Research Hospital, Kastamonu University

Language: English

Topic: Cardiac tumors and thrombi

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $2,890