Dual-Action NSAID-Gold(I) Alkynyl Hybrids for Synergistic Anti-Inflammatory and Anticancer Therapy of Colorectal Cancer

Year: 2026

Type: article

Abstract: transcription, highlighting a post-transcriptional anti-inflammatory action. These results support NSAID-derived alkynyl gold(I) complexes as promising multitarget agents for colorectal cancer intervention, combining disruption and COX-2 modulation.

Source: Inorganic Chemistry

DOI: 10.1021/acs.inorgchem.5c05908

Authors: Javier Sáez, Luis Vicente Herrera-Marcos, María Jesús Rodríguez-Yoldi, M. Concepción Gimeno, Elena Cerrada

Institutions: Universidad de Zaragoza, Instituto de Síntesis Química y Catálisis Homogénea, Spanish Biomedical Research Centre in Physiopathology of Obesity and Nutrition, Instituto de Investigación Sanitaria Aragón

Language: English

Topic: Metal complexes synthesis and properties

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,500

Funders: Ministerio de Ciencia, Innovación y Universidades, Universidad de Zaragoza, Gobierno de Aragón, Servier, Centro de Investigación Biomédica en Red-Fisiopatología de la Obesidad y Nutrición, Agencia Estatal de Investigación, Interreg

OpenAlex ID: W7141415352