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Metastatic Oropharyngeal Squamous Cell Carcinoma to the Colon: A Rare Cause of Acute Lower Gastrointestinal Bleeding

Year: 2026

Type: article

Abstract: Gastrointestinal (GI) bleeding is a common reason for hospitalization with many potential etiologies. A primary malignancy or metastatic lesion to any location in the GI tract can cause bleeding. Oropharyngeal squamous cell carcinoma (OPSCC) typically spreads to local lymph nodes, the lungs, or liver. Rarely, OPSCC metastasizes to the small intestine and colon. We present a case of intestinal metastatic human papillomavirus-associated OPSCC, highlighting the need to consider this pathology in patients with previously diagnosed OPSCC presenting with acute GI bleeding.

Source: ACG Case Reports Journal

DOI: 10.14309/crj.0000000000002044

Authors: Ashley Matias, Lindsay Jayne, Christopher Jayne, Jessica Corder, Erik Shanahan, Allison Bush

Institution: Naval Medical Center Portsmouth

Language: English

Topic: Metastasis and carcinoma case studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7141436929

FWCI:

Cites: 11

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