Work

Formulation of amorphous solid dispersion of clofazimine, an extremely water-insoluble basic drug, via hot-melt extrusion by applying acid-base supersolubilization principle

Year: 2026

Type: article

Source: International Journal of Pharmaceutics

DOI: 10.1016/j.ijpharm.2026.127063

Authors: Mufaddal H. Kathawala, Hari P. Kandagatla, Alex Avdeef, Martin Kuentz, Tatjana Ž. Verbić, Abu T.M. Serajuddin

Institutions: St. John's University, Pharmacologie de la circulation cérébrale, FHNW University of Applied Sciences and Arts Northwestern Switzerland, University of Belgrade

Language: English

Topic: Drug Solubulity and Delivery Systems

Subfield: Pharmaceutical Science

Field: Pharmacology, Toxicology and Pharmaceutics

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: green

Funders: BASF, St. John's University

OpenAlex ID: W7164345501

FWCI: 6.921

Cites: 42

Cited by: 2

Related to: 10