Work

Epidemiology, antimicrobial resistance transmission, and One Health–based prevention of non-typhoidal Salmonella and Campylobacter infections: an updated literature review

Year: 2026

Type: article

Abstract: remain leading causes of bacterial gastroenteritis worldwide, with a disproportionate burden in low- and middle-income regions. This updated review synthesizes current evidence on their epidemiology, antimicrobial resistance (AMR) dynamics, and the role of genomic epidemiology within a One Health framework. The global expansion of multidrug-resistant clones, driven largely by antimicrobial use in agriculture, increasingly compromises therapeutic options. Advances in whole-genome sequencing (WGS) have enhanced outbreak detection, source attribution, and tracking of AMR gene transmission across human, animal, and environmental reservoirs. Recent large-scale genomic analyses further clarify the temporal evolution and international dissemination of high-risk lineages. We argue that effective mitigation requires coordinated genomic surveillance, strengthened antimicrobial stewardship, and targeted interventions across the food chain. Implementing genomics-informed, cross-sectoral strategies under the One Health paradigm is essential to reduce disease burden and contain the spread of resistance.

Source: Frontiers in Microbiology

DOI: 10.3389/fmicb.2026.1809070

Authors: Guiliang Zheng, Lingling Chen, Guanghui Dong, Kun Ye, Zhe Liu, Lei Wang

Institutions: Shandong Agricultural University, Tianjin Medical University, Sun Yat-sen University, The People's Hospital of Guangxi Zhuang Autonomous Region

Language: English

Topic: Salmonella and Campylobacter epidemiology

Subfield: Food Science

Field: Agricultural and Biological Sciences

Domain: Life Sciences

SDGs: Good health and well-being, Zero hunger

Open Access status: gold

Estimated APC paid: $3,801