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Tezepelumab Reduces Alarmin Cytokine Levels in Upper Airway Epithelial Cells in Patients With Severe Asthma

Year: 2026

Type: article

Abstract: Summary Nasal epithelial cell alarmin cytokine levels are reduced in patients with severe asthma following tezepelumab. This is the first report showing nasal alarmin cytokine protein expression depletion following biologics.

Source: Clinical & Experimental Allergy

DOI: 10.1111/cea.70294

Authors: Hazel Marriott, Adil Adatia, Subhabrata Moitra, Paige Lacy

Institutions: University of Alberta, Ahmedabad University

Language: English

Topic: Asthma and respiratory diseases

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Estimated APC paid: $4,760

Funder: AstraZeneca Canada

OpenAlex ID: W7141912232

FWCI: 4.06

Cites: 9

Cited by: 1

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