Work

Evaluation of the MEFIER Score in Identifying Patients at High Risk of Endocarditis in Enterococcus faecalis Bacteremia

Year: 2026

Type: article

Study design: Observational Study

Abstract: In a retrospective cohort of 549 Enterococcus faecalis bacteremia episodes, the MEFIER score showed poor rule-out performance (negative likelihood ratio of 0.69), misclassifying 60% of IE episodes as low-risk. In contrast, DENOVi score achieved a low negative likelihood ratio (0.07), misclassifying only 5% while limiting unnecessary echocardiography.

Source: Open Forum Infectious Diseases

DOI: 10.1093/ofid/ofag184

Authors: Virgile Zimmermann, Nicolas Fourré, Pierre Monney, Georgios Tzimas, Laurence Senn, Lars Niclauss, Matthias Kirsch, Benoit Guery, Matthaios Papadimitriou-Olivgeris

Institutions: Centre Hospitalier Universitaire Vaudois, University of Lausanne, Hôpital du Valais

Language: English

Topic: Infective Endocarditis Diagnosis and Management

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $4,053

Funders: Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Schweizerische Herzstiftung

Awards: G1936438226, G5430677018

OpenAlex ID: W7141923501

FWCI: 4.471

Cites: 19

Cited by: 1

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