Work

Nitroxoline-O-protected derivatives inhibit MetAP2 and activate ATF4 through mTORC1 to inhibit cancer cell growth

Year: 2026

Type: article

Source: Bioorganic & Medicinal Chemistry Letters

DOI: 10.1016/j.bmcl.2026.130642

Authors: Michael J. Williams, Conor T. Ronayne, Tanner J. Schumacher, Kayla M. Johnson, Matthew D. Wittmer, Joseph L. Johnson, Grant W. Anderson, Venkatram R. Mereddy

Institution: University of Minnesota, Duluth

Language: English

Topic: PI3K/AKT/mTOR signaling in cancer

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: University of Minnesota, Randy Shaver Cancer Research and Community Fund

OpenAlex ID: W7142039127

FWCI:

Cites: 16

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Related to: 10