Maternal low-sodium diet impairs hippocampal neurogenesis and cognition in adult mouse offspring
Year: 2026
Type: article
Abstract: An adverse perinatal environment results in increased risk of long-term health morbidity. Pregnancy and lactation are common times for women to alter their diets. Maternal low-sodium diet resulted in impaired offspring spatial memory and learning associated with hippocampal neurogenesis. Adequate maternal sodium intake is essential for neurodevelopment of offspring.
Institutions: Children's Mercy Hospital, Medical College of Wisconsin
Language: English
Subfield: Developmental Neuroscience
Field: Neuroscience
Domain: Life Sciences
Open Access status: green
Funders: Advancing a Healthier Wisconsin Endowment, Medical College of Wisconsin, Children's Mercy Hospital, National Institutes of Health, National Heart, Lung, and Blood Institute, National Institute of Diabetes and Digestive and Kidney Diseases, National Center for Advancing Translational Sciences, Eunice Kennedy Shriver National Institute of Child Health and Human Development
Awards: G2383519555, G5181251264, Clinical and Translational Science Award, G8325781320, Regulation of Invasive Trophoblast Cell Lineage Development, Angiotensin receptor G protein signal switching in AgRP neurons in cardiometabolic control, Impact of Early Life Sodium Intake on Growth and Metabolism – Role of Hypothalamic Mechanisms
OpenAlex ID: W7142313624