Work

The effect of nasal patency and anatomy during asymmetrical nasal high flow

Year: 2026

Type: article

Abstract: The asymmetrical cannula interface used during nasal high flow (NHF) causes unequal occlusion of the nares. This study demonstrates that physiological changes of nasal patency at the internal nasal valve, known as the nasal cycle, do not affect ventilation during NHF. In contrast, anatomical variability, such as differences in the cross-sectional area of the nares or severe nasal septum deviation, may substantially influence the generated pressure and could produce physiologically relevant effects during therapy.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00068.2026

Authors: Monique Rees, Fernando Vieira, Sasi Bhushan Yarragudi, Matthew Barnes, Stanislav Tatkov

Institutions: Fisher & Paykel Healthcare (New Zealand), Massey University

Language: English

Topic: Respiratory Support and Mechanisms

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funder: Fisher and Paykel Healthcare