Presentation, care, and outcomes of patients with NSTEMI according to World Bank country income classification

Year: 2026

Type: article

Abstract: Background The majority of NSTEMI burden resides outside high-income countries (HICs). We describe presentation, care, and outcomes of NSTEMI by country income classification. Methods and results Prospective cohort study including 2947 patients with NSTEMI from 287 centres in 59 countries, stratified by World Bank country income classification. Quality of care was evaluated based on 12 guideline-recommended care interventions. The all-or-none scoring composite performance measure was used to define receipt of optimal care. Outcomes included in-hospital acute heart failure, stroke/transient ischaemic attack, and death, and 30-day mortality. Patients admitted with NSTEMI in low to lower-middle-income countries (LLMICs), compared with patients in HICs, were younger, more commonly diabetic, and current smokers, but with a lower burden of other comorbidities, and 76.7% met very high risk criteria for an immediate invasive strategy. Invasive coronary angiography use increased with ascending income classification (LLMICs, 79.2%

Source: DiRROS repository (University of Maribor)

Authors: Nadarajah, Ramesh, Ludman, Peter, Laroche, Cécile, Appelman, Yolande, Brugaletta, Salvatore, Budaj, Andrzej J, Bueno, Héctor, Huber, Kurt, Kunadian, Vijay, Leonardi, Sergio, Lettino, Maddalena

Language: English

Topic: Acute Myocardial Infarction Research

Subfield: Cardiology and Cardiovascular Medicine

Field: Medicine

Domain: Health Sciences

SDGs: Good health and well-being, Reduced inequalities

Open Access status: green

Funders: Amgen, Bristol-Myers Squibb, Eli Lilly and Company, Pfizer, AstraZeneca, Bayer, Sanofi, Boston Scientific Corporation, ResMed, European Society of Cardiology, Servier, Novartis Pharma, Abbott Vascular, Daiichi Sankyo Europe

OpenAlex ID: W7142582491