Work

An optimized translating ribosome affinity purification protocol for low-abundance Drosophila tissues

Year: 2026

Type: article

Abstract: genetics across developmental stages, genetic backgrounds, and disease models, and can be adapted for rare genotypes, other tissues and model systems requiring high sensitivity.

Source: iScience

DOI: 10.1016/j.isci.2026.115530

Authors: Leonor Miller-Fleming, Wing Hei Au, Alexander J. Whitworth

Institutions: University of Cambridge, MRC Mitochondrial Biology Unit

Language: English

Topic: RNA and protein synthesis mechanisms

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,240

Funders: Medical Research Center, Hamad Medical Corporation, Motor Neurone Disease Association, Medical Research Council, European Research Council, National Health and Medical Research Council

Awards: The role of axonal mRNA translation in Amyotrophic Lateral Sclerosis (resubmission), G150779926, G3108382839, Identifying Novel Molecular Targets for Treating Chronic Pain., G8860458140

OpenAlex ID: W7143345098

FWCI:

Cites: 40

Cited by:

Related to: 10