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Primary Bone Lymphoma: A Case Report

Year: 2026

Type: article

Abstract: A 26-year-old woman presented with three months progressive right hip pain and difficult ambulation, which was subsequently diagnosed as germinal center–type diffuse large B-cell lymphoma in the right femoral head, neck and upper-midshaft region without any nodal or visceral lesions. Primary bone lymphoma (PBL) is an uncommon extranodal lymphoma representing approximately 1% of all lymphomas and 3–7% of malignant primary bone tumors. While it typically affects older adults, occurrences in younger patients are rare and may lead to delayed recognition. PBL may radiologically resemble benign bone disease, emphasizing the importance of clinical suspicion. Diagnosis requires multimodal evaluation, with chemoimmunotherapy remaining the primary treatment.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.19324954

Author: Corazon A Ngelangel1,3*, Donnel AT Rubio2,3, Thomas Jason A Ngelangel3, Kaye Angeli H Gonzales-So1, Jennifer Sandoval-Tan1

Language: English

Topic: Lymphoma Diagnosis and Treatment

Subfield: Pathology and Forensic Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7143501495

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