Work

Visible-Light-Mediated Metal-Free Desulfonylative Silylation for Alkenyl and Alkynylsilanes with Silacarboxylic Acids

Year: 2026

Type: article

Abstract: High Resolution Image Download MS PowerPoint Slide Herein, we report a brand-new example of visible-light-mediated desulfonylative silylation between silacarboxylic acids and α,β-unsaturated aryl sulfones. Valuable alkenyl and alkynylsilane skeletons had been efficiently synthesized, and abundant substrate sources made the reaction more alternative and widely applicable, simultaneously avoiding limitations from conventional methodologies. Meanwhile, the gram-scale reaction with a hydroxyl-containing substrate and successful involvement of dehydrocholic acid derivatives further demonstrated the practicality of this desulfonylative silylation process. Mechanically, a cascade process with silyl radical addition and PhSO 2 – elimination was proposed.

Source: ACS Omega

DOI: 10.1021/acsomega.5c11976

Author: Zhao-Zhao Zhou

Institutions: Nanchang University, Nanchang Normal University, State Key Laboratory of Food Science and Technology

Language: English

Topic: Radical Photochemical Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: gold

Estimated APC paid: $1,935

Funders: National Natural Science Foundation of China, Natural Science Foundation of Jiangxi Province