Work

Taming autoimmunity: Alpha-1 antitrypsin overexpressing mesenchymal stromal cells promote regulatory T cell crosstalk to reverse diabetes

Year: 2026

Type: article

Source: Molecular Therapy

DOI: 10.1016/j.ymthe.2026.03.032

Authors: Hua Wei, Wenyu Gou, Judong Kim, Suganya Subramanian, Tiffany Yeung, Paramita Chakraborty, Ahmed Lotfy, Shikhar Mehrotra, Stefano Berto, Charlie Strange, Hongjun Wang

Institutions: Medical University of South Carolina, Ralph H. Johnson VA Medical Center

Language: English

Topic: Mesenchymal stem cell research

Subfield: Genetics

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

Funders: U.S. Department of Veterans Affairs, Medical University of South Carolina, National Institutes of Health, National Institute of Diabetes and Digestive and Kidney Diseases

Awards: G2387291307, G3276194190, G330187846, G4223979924, Novel Gene and Stem Cell Therapy for Type 1 Diabetes, G5787602321, G7417865685, Sex disparities in aldosterone-dependent renal Na+ transport and blood pressure control, Cellular Therapy for Type 1 Diabetes using Mesenchymal Stem Cells, Autologous BM-MSCs and Islet Co-transplantation to Enhance Islet Survival and Function in TP-IAT Patients, Medical University of South Carolina - Cancer Center Support Grant, COBRE in Neurodevelopment and Its Disorders

OpenAlex ID: W7143696918

FWCI: 3.867

Cites: 88

Cited by: 1

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