Work

Purulent meningitis in X-linked agammaglobulinemia: one case report

Year: 2026

Type: article

Abstract: X-linked agammaglobulinemia (XLA) is characterized by a triad of primary immunodeficiency, profound hypogammaglobulinemia due to absent antibody production, and a consequent predisposition to severe and recurrent bacterial infections. We employed next-generation sequencing (NGS) on patients with immunodeficiency and their immediate relatives to facilitate the diagnosis and genetic counseling of XLA, thereby improving our understanding of this rare disorder.

Source: Frontiers in Immunology

DOI: 10.3389/fimmu.2026.1704590

Authors: Anyi Ba, Lijiang Wang, Ruifang Ren, Ting C. Zhao, Wenyu Di, Jinggui Song

Institutions: Henan Medical University, Rhode Island Hospital

Language: English

Topic: Immunodeficiency and Autoimmune Disorders

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,801