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In situ evaluation of the bleaching efficacy of experimental hydrogen peroxide hydrogel with MnO‐doped Biosilicate activated by violet LED light

Year: 2026
Type: article
Abstract: Hydrogen peroxide (HP) at 35% is effective for dental bleaching but may reduce enamel mineral content and induce structural changes. This study developed a bleaching‐hydrogel containing 6%HP and manganese‐oxide–doped Biosilicate (MnO_BioS), activated by violet LED, under in situ conditions. Pigmented enamel blocks were attached to palatal devices ( n = 12) and kept intraorally for 15 days, being removed only for bleaching sessions. Experimental groups were as follows: 35%HP (positive control) and 6%HP gel containing BioS or MnO_BioS (0/10 wt%), with or without violet LED irradiation. Bleaching consisted of three 30‐min sessions with 7‐day intervals. Color change (Δ E 00 ), whiteness index (ΔWI D ), color coordinates (Δ L *, Δ a *, Δ b *), surface hardness recovery (%SHR), and enamel inorganic content (CO 3 2− /PO 4 3− ratio by Fourier‐transform infrared) were evaluated at baseline ( T 0 ) and after treatment ( T 1 ), with scanning electron microscopy analysis at T 1 . Data were analyzed using analysis of variance and Tukey's‐test ( α = 0.05). 6%HP_MnO_BioS_LED showed the highest bleaching effectiveness (Δ E 00 = 8.90 ± 1.18; ΔWI D = 20.86 ± 3.26), surpassing 35%HP in ΔWI D (15.53 ± 1.33) and showing comparable Δ E 00 (6.48 ± 1.81). MnO_BioS groups increased enamel CO 3 2− /PO 4 3− ratios after bleaching (0.475 ± 0.02; 0.466 ± 0.01) compared with baseline (0.431 ± 0.01; 0.429 ± 0.01; p < 0.05). Hardness recovery improved (%SHR = 4.14 ± 1.88; 5.45 ± 2.54), whereas it decreased in 35%HP (−1.32 ± 1.67) and 6%HP_LED (−2.60 ± 0.96). 6%HP hydrogel containing MnO_BioS activated by violet LED enhanced bleaching efficacy while preserving enamel mineral‐related parameters.
Language: English
Subfield: Orthodontics
Field: Dentistry
Open Access status: hybrid
Estimated APC paid: $4,220
OpenAlex ID: W7144000079
FWCI:
Cites: 20
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