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Fluid balance, kidney function, and acute kidney injury risk in healthy men and women during simulated work-related heat stress

Year: 2026

Type: article

Abstract: Although men are often thought to be at greater risk of dehydration during work-related heat stress due to lower fluid intake, the impact of biological sex on fluid balance remains unclear. This study shows that when cool fluids are available, men and women maintain similar fluid balance regardless of menstrual cycle phase, suggesting that sex does not influence dehydration risk during simulated work-related heat stress.

Source: Journal of Applied Physiology

DOI: 10.1152/japplphysiol.00822.2025

Authors: Jessica A. Freemas, Curtis S. Goss, Riley Ables, Tyler B. Baker, Georgie Bruinvels, Toby Mündel, Bruce J. Martin, Stephen J. Carter, Robert F. Chapman, Omkar M. Khandpekar, Roger S. Zoh, Zachary J. Schlader

Institutions: Indiana University Bloomington, Indiana University, Brock University, Indiana University School of Medicine, Indiana University Health, Indiana University Melvin and Bren Simon Comprehensive Cancer Center

Language: English

Topic: Thermoregulation and physiological responses

Subfield: Physiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: hybrid

Funders: American College of Sports Medicine, Centers for Disease Control and Prevention

Award: OCCUPATIONAL SAFETY AND HEALTH RESEARCH (R01)

OpenAlex ID: W7144106232

FWCI: 7.848

Cites:

Cited by: 2

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