Work

Poly(ADP-ribose) glycohydrolase inhibition sequesters NAD+ to potentiate the metabolic lethality of alkylating chemotherapy in IDH-mutant tumor cells

Year: 2020

Type: article

Source: Institutional Repositories DataBase (IRDB)

DOI: 10.1158/2159-8290.cd-20-0226

Authors: Nagashima, Hiroaki, Lee, Christine K., Tateishi, Kensuke, Subramanian, Megha, Rafferty, Seamus, Melamed, Lisa, Miller, Julie J., Wakimoto, Hiroaki, Cahill, Daniel P.

Institutions: Harvard University, Yokohama City University

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7146085531

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