Supplemental Figure 3 from Defective DNA Damage Response Is a Targetable Therapeutic Vulnerability in ESR1-Mutant Breast Cancer
Year: 2026
Type: supplementary-materials
Abstract: The ESR1m defective RSR signature does not predict disease specific or overall survival in the METABRIC ER-negative breast cancer cohort a. Kaplan-Meier plots of disease specific survival (DSS) and b. overall survival (OS) for the ESR1m defective RSR signature in the top 50% versus bottom 50% of signature expressing ER-negative patients (n=440) from the METABRIC cohort.
Authors: Sarah K. Herzog, Jessica H. Stevens, Guowei Gu, Sandra L. Grimm, Kloma Cardoza, Autumn G.M. Hawkins, Hangqing Lin, Daniela Ramos, Amanda R. Beyer, David G. Edwards, Derek Dustin, Harry J. Yang, Nicole Liang, Ashfia F. Khan, Tasneem Bawa-Khalfe, Daniel J. McGrail, Shiaw-Yih Lin, Cristian Coarfa, Suzanne A.W. Fuqua
Language: English
Subfield: Cancer Research
Domain: Life Sciences
Open Access status: gold
OpenAlex ID: W7146946074