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Single-molecule approaches to study G-quadruplex, R-loop, and protein interactions

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Year: 2026
Type: review
Source: Current Opinion in Structural Biology
DOI: 10.1016/j.sbi.2026.103255
Authors: Sunghyun Cho, Sua Myong
Institutions: Boston Children's Hospital, Harvard University
Language: English

Topic: DNA and Nucleic Acid Chemistry
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences

Open Access status: green

Funders: National Institutes of Health, National Institute on Aging, National Cancer Institute, National Institute of Neurological Disorders and Stroke
Awards: Quantitative Analysis of G-Quadruplex Folding and its Role in Gene Expression, Molecular Assembly and Disassembly of RNA-Protein Complexes Implicated in ALS, Roles of Telomeric Oxidative DNA Lesions in Telomere Length Regulation, Gene Expression Modulated by G4, R-loop and DNA Supercoiling
OpenAlex ID: W7146947213
FWCI: 0.876
Cites: 55
Cited by: 1
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