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Non-oral tissue regeneration, angiogenesis, and healing with enamel matrix derivative

Year: 2026

Type: article

Abstract: Introduction: Enamel matrix derivative (EMD) is a biomaterial derived from developing porcine tooth structures, primarily composed of amelogenins, which have been shown to regulate fibroblast and osteoblast activity. While EMD is well-established in periodontal regeneration, its potential in non-oral tissue healing and regeneration is less explored. This review aims to systematically assess the existing literature on the application of EMD in non-oral tissue regeneration, evaluating its biological effects, mechanisms of action, and potential clinical applications.

Source: Academia Biology

DOI: 10.20935/acadbiol8227

Authors: Omar Zada, Carolina Serrano-Larrea, Marcel Karperien, Egbert J. D. Veen

Institutions: Medisch Spectrum Twente, University of Twente

Language: English

Topic: Periodontal Regeneration and Treatments

Subfield: Urology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7146958362

FWCI:

Cites: 71

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