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Association between soft drink consumption and depression mediated by gut microbiome: a perspective

Year: 2026

Type: article

Abstract: partially mediated the soft drink-depression association, explaining approximately 4% of the association. Soft drink consumption is associated with increased depression risk through multiple biological pathways involving inflammation, metabolic dysregulation, and gut microbiome alterations. Modest effect sizes suggest the involvement of multiple interconnected mechanisms. Public health interventions to limit sugar-sweetened beverage consumption are recommended to improve physical and mental health. Healthcare providers should consider dietary assessment and counselling as part of depression prevention and treatment strategies.

Source: East Asian Archives of Psychiatry

DOI: 10.12809/eaap25136

Author: Sankar S Sailesh

Institutions: Amrita Institute of Medical Sciences and Research Centre, Amrita Vishwa Vidyapeetham

Language: English

Topic: Gut microbiota and health

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7147159002

FWCI: 1.939

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Cited by: 1

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