Work

49P Correlation of cell counts, tumor mass, and histopathologic phenotype in serous ovarian carcinoma: Implications for TILs therapy development as an ATMP

Year: 2026

Type: article

Abstract: Tumor-infiltrating lymphocyte (TIL) therapies are a promising strategy for ovarian cancer as advanced therapy medicinal products (ATMPs). Their efficacy depends on the quantity and quality of cells in the starting material. Automated quantitative assessment enables objective, reproducible measurements. Results were cross-validated by flow cytometry (gold standard) on the MaxQuant Miltenyi platform, ensuring reliability.

Source: ESMO Open

DOI: 10.1016/j.esmoop.2026.106154

Authors: J. Marynowska, M. Gutek, A. Biernacka, Z. Usmial

Institution: The Maria Sklodowska-Curie National Research Institute of Oncology

Language: English

Topic: Ovarian cancer diagnosis and treatment

Subfield: Reproductive Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $3,910