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Supplemental Figure 3 from Altered MDC1 Interactions and Dysfunctional DNA Repair in Lobular Breast Cancer Confers Sensitivity to PARP Inhibition

Year: 2026

Type: supplementary-materials

Abstract: ER target gene sets and FOXA1 vs MDC1 activity are distinct across gene expression clusters, cell cycle status, and treatment group

DOI: 10.1158/0008-5472.31923149

Authors: Joseph L. Sottnik, Madeleine T. Shackleford, Camryn S. Nesiba, Amanda L. Richer, Zoe Fleischmann, Jordan M. Swartz, Carmen E. Rowland, Maggie Musick, Rui Fu, Logan R. Myler, Patricia L. Opresko, Sanjana Mehrotra, Ethan S. Sokol, Jay R. Hesselberth, Jennifer R. Diamond, Matthew J. Sikora

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7147335989

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