Work

Supplementary Figure 1 from Discovery of Potent and Brain-Penetrable Tubulin Inhibitors that Effectively Suppress Breast Cancer Brain Metastasis

Year: 2026

Type: supplementary-materials

Abstract: Supplementary Figure 1. SB-216 and SP-1-39 potently inhibit tumor cell growth in TNBC TxR sublines, and TxR cells up-regulate P-gp (ABCB1) expression at the mRNA and protein levels.

DOI: 10.1158/1535-7163.31924787

Authors: Raisa I. Krutilina, Kelli L. Adeleye, Hilaire C. Playa, Satyanarayana Pochampally, Souvik Banjeree, Damilola Oluwalana, Mir Shahriar Kamal, Di Tian, Duane D. Miller, Wei Li, Tiffany N. Seagroves

Language: English

Topic: Drug Transport and Resistance Mechanisms

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

OpenAlex ID: W7147434029

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