Work

Discovery of a chimeric transposase-transposon system for advanced genome engineering

Year: 2026

Type: article

Abstract: system with regard to cell-specific productivity. These findings introduce a significant addition to the field of semi-targeted transgene integration technologies, offering substantial potential for enhancing biologics manufacturing.

Source: iScience

DOI: 10.1016/j.isci.2026.115548

Authors: Daniel Heinzelmann, Franziska Reuss, Nikolas Zeh, Robin Nilson, Emely Walker, Juergen Fieder, Benjamin Lindner, Benjamin Renner, Patrick Schulz, Simon Fischer, Moritz Schmidt

Institution: Boehringer Ingelheim (Germany)

Language: English

Topic: CRISPR and Genetic Engineering

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: gold

Estimated APC paid: $3,240

Funder: Boehringer Ingelheim

OpenAlex ID: W7147528442

FWCI:

Cites: 47

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