Work

The protein RAB5IF promotes BDNF signaling by stimulating the SUMOylation of Gα i1/3 to reduce depressive-like behaviors in mice

Year: 2026

Type: article

Source: Science Signaling

DOI: 10.1126/scisignal.aec8898

Authors: Xin Shi, Han-qi Liu, Shi-zhong Cai, Yi-hang Shen, Jin-long Chai, Mei-qing Zhang, Chen-yang Xu, Zhi-qing Zhang, John Marshall, Cong Cao

Institutions: Second Affiliated Hospital of Soochow University, Soochow University, Children's Hospital of Suzhou University, Brown University

Language: English

Topic: Treatment of Major Depression

Subfield: Pharmacology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

Funders: National Natural Science Foundation of China, China Postdoctoral Science Foundation, Government of Jiangsu Province

Awards: G1149821553, G2381354276, G2477956775, G3146100939, G3308476284, G3401494339, G6971884222, G8162403328, G8644340317

OpenAlex ID: W7147583117

FWCI: 3.862

Cites: 59

Cited by: 1

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