Site-specific methylation of SRSF2 P95H by SETD2 inhibits MDSC-mediated proinflammatory niche formation in mouse models of myelodysplastic syndrome
Year: 2026
Type: article
Source: Science Translational Medicine
Authors: Zi-Juan Li, Mu-Ying Zhao, Roujia Wang, Na Liu, Cheng-Long Hu, Binhe Chang, Fang Hu, Xi-Ya Li, Chun-Hui Xu, Ping Liu, Bing-Yi Chen, Shu-Bei Chen, Yong Wang, Qi-Jing Li, Bu-Sheng Xue, Chuhan Deng, Xinchi Chen, Yiyi Ren, Jia-Cheng Jin, Xiao Yan, Yuanliang Zhang, Robert Peter Gale, Jianfei Fu, Qun-ling Zhang, Xiaoning Wang, Qiuhua Huang, Yan Liu, Ju Qiu, Jun Qin, Xueshi Ye, Jin Zhang, Yang Liang, Zhu Chen, Sai-Juan Chen, Peng-Cheng He, Chun-Kang Chang, Xiao-Jian Sun, Lan Wang
Institutions: Shanghai Jiao Tong University, Ruijin Hospital, Shanghai Institute of Nutrition and Health, Shanghai Institute of Hematology, University of Chinese Academy of Sciences, State Key Laboratory of Medical Genomics, Shanghai Sixth People's Hospital, Second Military Medical University, Changhai Hospital, Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, First Affiliated Hospital of Xi'an Jiaotong University, Ningbo University, Imperial College London, Tongji University, Shanghai Medical College of Fudan University, Fudan University, Northwestern University, Sir Run Run Shaw Hospital, Zhejiang University
Language: English
Subfield: Hematology
Field: Medicine
Domain: Health Sciences
Open Access status: closed
Awards: G2616631619, Mutant p53 rejuvenates aged stem cells through modulating epigenetic regulators, G3427301363, G5205781744, Molecular mechanisms underlying clonal expansion of hematopoietic stem cells, G8487579138, G8900270407, Molecular mechanism underlying clonal expansion of hematopoietic stem cells
OpenAlex ID: W7147657574