Work

Histopathological analysis of esophageal biopsies obtained via endoscopy at a tertiary care hospital

Year: 2026

Type: article

Abstract: Background: Esophageal lesions encompass a wide spectrum of non-neoplastic, pre-neoplastic, and malignant conditions, with endoscopic biopsy serving as the cornerstone of diagnosis. Aims and Objectives: The aims and objectives of this study were to study the histopathological spectrum of esophageal lesions and correlate malignant lesions with age, sex, and clinical presentation. Materials and Methods: A descriptive histopathological study was conducted on 80 endoscopic esophageal biopsy specimens. Lesions were classified and correlated with demographic parameters and clinical features. Results: Neoplastic lesions were identified in 52 cases, of which 49 were malignant. Squamous cell carcinoma was the predominant malignancy, most commonly affecting males aged 61–70 years. Dysphagia was the most frequent presenting symptom. Conclusion: Histopathological evaluation of endoscopic esophageal biopsies provides definitive diagnosis and valuable clinicopathological correlation, emphasizing its role in early detection and management of esophageal malignancies.

Source: Asian Journal of Medical Sciences

DOI: 10.71152/ajms.v17i4.5196

Authors: Jyoti B Gadhavee, Rajul R Shah, Mananshi R Shah

Institution: Narendra Modi Medical College

Language: English

Topic: Esophageal Cancer Research and Treatment

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $200