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Formulation of Vitamin A Tracer Doses for Administration to Human Subjects using Retinol Isotope Dilution Technique

Year: 2026

Type: article

Abstract: C] with >95% all-trans isomeric purity and >99% isotopic enrichment. The preparation of the vitamin A stable isotope tracers involves dissolving the tracer in edible vegetable oil through sonication and heat. Tracers need to be prepared at a concentration that is well within the volumetric limits of the delivery system. Finally, the tracer is aliquoted into sterile amber glass vials, and tracer concentrations are confirmed spectrophotometrically.

Source: Journal of Visualized Experiments

DOI: 10.3791/69240

Authors: Georg Lietz, Anthony Oxley

Institutions: University of Newcastle Australia, Newcastle University

Language: English

Topic: Retinoids in leukemia and cellular processes

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

Open Access status: green

OpenAlex ID: W7147697661

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