Work

Microwave-assisted sample preparation: A review of 50 years of achievements and trends

Year: 2026

Type: article

Abstract: BACKGROUND: Microwave-assisted digestion is the state of the art in sample preparation for elemental analysis and has been widely used for a diversity of samples. This status has been achieved through significant conceptual, technological, and applicative landmarks over its 50 years of development. However, classical approaches are still widely used, underscoring the need for broader dissemination of microwave-assisted digestion. RESULTS: Challenges and opportunities for improvement remain, particularly in advancing greener, faster, and more efficient microwave-assisted methods. SIGNIFICANCE: A discussion of key developments and future directions in celebration of its 50th anniversary is presented here, aiming to contribute to further advances in the field.

Source: Analytica Chimica Acta

DOI: 10.1016/j.aca.2026.345473

Authors: Fábio R.P. Rocha, Joaquim A. Nóbrega

Institutions: Universidade de São Paulo, Universidade Federal de São Carlos

Language: English

Topic: Analytical chemistry methods development

Subfield: Analytical Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,270

Funders: Fundação de Amparo à Pesquisa do Estado de São Paulo, Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Conselho Nacional de Desenvolvimento Científico e Tecnológico