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Cognitive Functioning, Anxiety, and Depression in Patients with Intracranial Tumors with and Without Aphasia

Year: 2026

Type: article

Abstract: Introduction: Cognitive impairment is the most common neurological disorder associated with brain tumors, which leads to linguistic communication damage. Anxiety and depression are among the most prevalent psychiatric comorbidities in this population. Objectives: To determine the level of cognitive functioning, anxiety, and depression in patients with intracranial tumors with and without aphasia. Subjects and methods: A prospective study was conducted on 91 patients with verified brain tumors which were hospitalized at the Clinic for Neurosurgery for one year period. The patients were assessed with Mini Mental State Examination, Beck’s depression inventory, and Beck’s anxiety inventory. The type and severity of aphasia were determined by the Boston Aphasia Test. Results: The highest number of patients, a total of 31 (37.3%), had moderate anxiety disorder. 30 patients (36.1%) had shown symptoms of moderate depression, and 33 (39.7%) had shown mild and moderate cognitive dysfunction. Conclusion: Anxiety, depression, and cognitive dysfunction were significantly more pronounced in subjects with aphasia.

Source: Journal Human Research in Rehabilitation

DOI: 10.21554/hrr.042618

Authors: Jasmina Klebic, Emir Tupkovic, Rusmir Softic, Mirela Duranovic, Aida Sehanovic, Ajna Softic, Senada Selmanovic, Amila Srabovic Tokic, Nedim Srabovic, Melika Klebic

Institutions: University Clinical Center Tuzla, University of Tuzla, University of Sarajevo, Sarajevo School of Science and Technology

Language: English

Topic: Cancer-related cognitive impairment studies

Subfield: Pulmonary and Respiratory Medicine

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7147804220

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