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Sirolimus Administration Does Not Affect Growth Parameters in Children with Vascular Anomalies Treated for 2 Years or More

Year: 2026

Type: article

Abstract: Sirolimus has been identified as an effective medication in patients of all ages diagnosed with various vascular anomalies. Although the medication’s safety and efficacy have been well published in the last decade, the effect of sirolimus on growth parameters (height and weight) has not been thoroughly analyzed. We performed a retrospective chart review over a large cohort of patients with vascular anomalies treated at our center. We found that sirolimus does not adversely affect growth in patients on consistent and long-term use of sirolimus when controlled for age and gender.

Source: Journal of Vascular Anomalies

DOI: 10.1097/jova.0000000000000139

Authors: Marisa Rao, Jesline Simon, Ionela Iacobas

Institutions: University of North Texas Health Science Center, University of Houston, Baylor College of Medicine, Texas Children's Hospital

Language: English

Topic: Vascular Malformations and Hemangiomas

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: diamond

OpenAlex ID: W7148527601

FWCI:

Cites: 10

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