Work

Epigenetic orchestration of sugar signaling in plant development and stress adaptation

Year: 2026

Type: article

Abstract: Sugars are not only metabolites but also signals that gate plant growth, fruit ripening, and stress responses. Carbon-sensing pathways (HEXOKINASE 1, TOR-SnRK1, and the sucrose Trehalose-6-phosphate pathway) reprogram gene expression by engaging DNA methylation, histone modification, chromatin remodeling, regulatory RNAs, and RNA modifications. Cutting-edge quantitative epigenomic and epitranscriptomic methods, integrated with novel bioinformatics tools, are driving unprecedented resolution in epigenetic landscape analysis. Benefitting from state-of-the-art technologies, we summarize epigenetic control points for pigmentation, softening, sugar–acid balance, and stress acclimation (e.g. SlDML2, PH5, RdDM-ABA modules). This synthesis underscores that decoding the sugar–epigenome interplay is key to understanding plant phenotypic plasticity and improving crop performance. Finally, we explore how leveraging epigenetic regulation via CRISPR-based epigenome editing, transgenerational inheritance patterns, and epigenomic biomarker-based (epibreeding) approaches holds promise for improving crop resilience and productivity.

Source: Horticulture Research

DOI: 10.1093/hr/uhag109

Authors: Ping Zhao, Yi Liu, Javeria Abid, Xingtan Zhang, Noor-ul Ain

Institutions: Agricultural Genomics Institute at Shenzhen, Chinese Academy of Agricultural Sciences

Language: English

Topic: Epigenetics and DNA Methylation

Subfield: Molecular Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Zero hunger

Open Access status: gold

Estimated APC paid: $2,960