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Diseases of the Esophagus: GERD, Achalasia, Barrett's Esophagus, and Schatzki Ring

Year: 2026

Type: article

Abstract: Esophageal disorders such as Gastroesophageal Reflux Disease (GERD), Achalasia, Barrett’s esophagus, and Schatzki ring represent major causes of morbidity worldwide. These conditions encompass functional, structural, and premalignant pathologies with overlapping symptoms but distinct pathophysiological mechanisms. This review integrates epidemiological trends (2010–2025), clinical features, diagnostic advancements, and therapeutic strategies. Special emphasis is placed on early detection, prevention of complications like esophageal adenocarcinoma, and the role of minimally invasive therapies. Advances in endoscopy, manometry, and pharmacotherapy have significantly improved outcomes and quality of life in patients with esophageal disorders.

Source: Zenodo (CERN European Organization for Nuclear Research)

DOI: 10.5281/zenodo.19382214

Authors: Kaiypov Abdumazhit, Sathe, Vishal, Ambarbande, Amol, Ganvir, Ayush

Institution: Osh State University

Language: English

Topic: Gastroesophageal reflux and treatments

Subfield: Gastroenterology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7148562709

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