Work

Transcatheter device closure of post–myocardial infarction ventricular septal rupture: A single-centre experience

Year: 2026

Type: article

Abstract: Post-myocardial infarction ventricular septal rupture is a rare but fatal mechanical complication, frequently complicated by cardiogenic shock. We conducted a single-centre retrospective cohort study of seventeen surgically declined patients who underwent transcatheter device closure between 2014 and 2025. Cardiogenic shock was present in 15 of 17 patients (88.2%). Device implantation achieved high technical success; however, early mortality remained substantial, with only six patients (35.3%) surviving beyond 30 days. Deaths were mainly due to refractory shock and multiorgan failure. Survival was associated with lower SCAI shock stage, preserved lactate clearance, and higher arterial pH, underscoring the importance of physiological status.

Source: Indian Heart Journal

DOI: 10.1016/j.ihj.2026.04.001

Authors: Praveen Chandra, Nagendra Singh Chouhan, Seenu Prasanth Adimoulame, Siddarth Varshney, Deepti Yadav, Anushree Kumbhalkar

Institutions: Medanta The Medicity, Medanta The Medicity

Language: English

Topic: Cardiac Structural Anomalies and Repair

Subfield: Surgery

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: gold

Estimated APC paid: $360