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[Corrigendum] Macrophage‑derived foam cells impair endothelial barrier function by inducing endothelial‑mesenchymal transition via CCL‑4

Year: 2026

Type: erratum

Abstract: figure 3. conditioned medium from m1-fcs stimulates haecs to undergo endmt in vitro.haecs were treated with conditioned medium from different phenotypic macrophages: conditioned medium from (a) m1, (B) m2a and (c) m2c macrophages and (d) m1, (e) m2a and (f) m2c-derived fcs at 1:1 ratio with eBm-2 for 6 days.haecs treated with conditioned medium from m1-fcs lost the typical cobblestone-like morphology and gained a spindle-like appearance.(g) Western blot analysis of endothelial and mesenchymal cell surface markers demonstrated that haecs incubated with conditioned medium from M1-FCs underwent EndMT.M1-FCs, M1 macrophage-derived foam cells; Con, control; Mφ, macrophage; FC, foam cell; VE-cadherin, vascular endothelial cadherin; α-SMA, α-smooth muscle actin; FSP-1, fibroblast-specific protein-1; EndMT, endothelial mesenchymal transition.

Source: International Journal of Molecular Medicine

DOI: 10.3892/ijmm.2026.5824

Authors: Ying Yang, Nian-Sang Luo, Ru Ying, Yong Xie, Jia-Yuan Chen, Xiao-Qiao Wang, Zhen-Jie Gu, Jing-Ting Mai, Wen-Hao Liu, Mao-Xiong Wu, Zhi-Teng Chen, Yong-Biao Fang, Hai-Feng Zhang, Zhi-Yi Zuo, Jing-Feng Wang, Yang-Xin Chen

Institutions: Sun Yat-sen University, Sun Yat-sen Memorial Hospital, First Affiliated Hospital of Nanchang University, Second Affiliated Hospital of Guangzhou Medical University

Language: English

Topic: Atherosclerosis and Cardiovascular Diseases

Subfield: Immunology

Field: Immunology and Microbiology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: hybrid

OpenAlex ID: W7148637148

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