Work

Rhodium‐Catalyzed Regioselective Addition of N ‐Hydroxyl Imides to Internal Alkynes

Year: 2026

Type: article

Abstract: An intermolecular rhodium‐catalyzed regioselective addition of N ‐hydroxyl imides to internal alkynes leads to branched O ‐allyl compounds, which can be readily transformed to allylic alcohols and O ‐allyl hydroxylamines after deprotection. Isotopic labeling experiments suggest a plausible reaction mechanism.

Source: Israel Journal of Chemistry

DOI: 10.1002/ijch.70014

Authors: Zi Liu, Bernhard Breit

Institution: University of Freiburg

Language: English

Topic: Catalytic Alkyne Reactions

Subfield: Organic Chemistry

Field: Chemistry

Domain: Physical Sciences

Open Access status: hybrid

Estimated APC paid: $4,650

Funder: Deutsche Forschungsgemeinschaft