Discovery of gene-alcohol interaction loci influencing blood pressure in 1.1 million individuals from multiple populations
Year: 2026
Type: preprint
Study design: Observational Study
Source: Research Square
Authors: Mary Feitosa, Karen Schwander, Clint Miller, Aldi Kraja, Amy Bentley, Michael Brown, Hannah de Hesselle, Raymond Noordam, Songmi Lee, Pavithra Nagarajan, Heming Wang, Ayush Giri, Farrah Ammous, Traci Bartz, Chiara Batini, Jean-Tristan Brandenburg, Max Breyer, Heather Cordell, Janie Corley, Latchezar Dimotrov, Anh Do, Jiawen Du, Franco Giulianini, Christopher Grace, Valborg Gudmundsdottir, Xiuqing Guo, Sarah Harris, Natalie Hasbani, Janina Herold, Keiko Hikino, Edith Hofer, Andrea Horimoto, Fang-Chi Hsu, Zhijie Huang, Anne Jackson, Chang Hoon Kang, Federica Laguzzi, Timo Lakka, Christophe Lefevre, Jian'an Luan, Leo-Pekka Lyytikäinen, Aline Meirhaeghe, Manon Muntaner, Masahiro Nakatochi, Giuseppe Giovanni Nardone, Ilja Nolte, Teresa Nutile, Nicholette Palmer, Amit Patki, Alessandro Pecori, Varun Rao, Anne Richmond, Mercedes Richter, Mihir Sanghvi, Aurora Santin, Heather Stringham, Fumihiko Takeuchi, Ye An Tan, Jingxian Tang, Maris Teder-Laving, Olga Trofimova, Stella Trompet, Peter van der Most, Ya Xing Wang, Zhe Wang, Yujie Wang, Wenyi Wang, Erin Ware, Stefan Weiss, Kenneth Westerman, Chenglong Yu, Wanying Zhu, Md Abu Yusuf Ansari, Pramod Anugu, Anna Argoty-Pantoja, John Attia, Bernhard Banas, Lydia Bazzano, Joshua Bis, Carsten Boger, Jennifer Brody, Ulrich Broeckel, Harry Campbell, Archie Campbell, Pasqualina Cennamo, William Checkley, Miao-Li Chee, Guanjie Chen, Yii-Der Chen, Kayesha Coley, Stacey Collins, Jean Dallongeville, Hithanadura Janaka de Silva, Charles Dupont, Todd Edwards, Christian Enzinger, Jessica Faul, Lilian Fernandes Silva, Adam Gepner, Anuj Goel, Mathias Gorski, Mariaelisa Graff, C. Charles Gu, Jiang He, Sami Heikkinen, Erin Hill-Burns, Adriana Hung, Steven Hunt, Marguerite Irvin, Mika Kähönen, Sharon Kardia, Minjung Kho, Heikki Koistinen, Ivana Kolčić, Pirjo Komulainen, José Eduardo Krieger, Lenore Launer, Daniel Levy, Jianjun Liu, Joseph McCormick, John McNeil, yuri milaneschi, Jaime Miranda, Kari North, Anniina Oravilahti, Alison Pattie, Patricia Peyser, Giulia Pianigiani, Leslie Raffel, Olli Raitakari, Michele Ramsay, Salil Redkar, Paul Redmond, Paul Ridker, Frits Rosendaal, Daniela Ruggiero, Tom Russ, Charumathi Sabanayagam, Alyssa Scartozzi, Reinhold Schmidt, Laura Scott, Rodney Scott, Susan Shenkin, Roelof Smit, Jennifer A. Smith, Zhi Da Soh, Beatrice Spedicati, David Stott, Quan Sun, Gerald Sze, E Shyong Tai, Paola Tesolin, Rima Triatin, Nataraja Sarma Vaitinadin, Rob van Dam, Julien Vaucher, Uwe Völker, Henry Völzke, Chaolong Wang, Helen Warren, Rajitha Wickremasinghe, Ko Willems van Dijk, Cancan Xue, Ken Yamamoto, Jie Yao, Mitsuhiro Yokota, Martina Zimmermann, Philippe Amouyel, Jennifer Below, Sven Bergmann, Antonio Bernabe-Ortiz, Michael Boehnke, Palwende Boua, LifeLines Cohort study, Donald Bowden, Daniel Chasman, Ching-Yu Cheng, Marina Ciullo, Maria Pina Concas, Simon R. Cox, Luc Dauchet, Ian Deary, Stephan Felix, Ervin Fox, Nora Franceschini, Barry Freedman, Paolo Gasparini, Giorgia Girotto, Vilmundur Gudnason, Caroline Hayward, Iris Heid, Elizabeth Holliday, Sahoko Ichihara, Catherine John, Jost Jonas, J Wouter Jukema, Mart Kals, Norihiro Kato, Bernard Keavney, Tanika Kelly, Markku Laakso, Paul Lacaze, Leslie Lange, Karin Leander, Seunggeun Lee, Terho Lehtimäki, Changwei Li, Ching-Ti Liu, Ruth Loos, brenda penninx, Alexandre Pereira, Ozren Polasek, Bruce Psaty, Rainer Rauramaa, Charles Rotimi, Jerome Rotter, Igor Rudan, Helena Schmidt, Xueling Sim, Harold Snieder, Klaus Stark, Chikashi Terao, Lynne Wagenknecht, Nicholas Wareham, Hugh Watkins, David Weir, Kristin Young, Wei Zhao, William Gauderman, Alanna Morrison, Myriam Fornage, Han Chen, Jeffrey O'Connell, Alisa Manning, Paul de Vries, Lisa de las Fuentes, Dabeeru Rao, Patricia Munroe, Michael Province, Thomas Winkler
Institutions: Washington University in St. Louis, University of Virginia, University of Mississippi Medical Center, National Human Genome Research Institute, The University of Texas Health Science Center at Houston, University of Regensburg, Leiden University Medical Center, Seoul National University, Brigham and Women's Hospital, Harvard University, Vanderbilt University Medical Center, University of Michigan, University of Washington, University of Leicester, Vanderbilt University, Newcastle University, University of Edinburgh, Wake Forest University Health Sciences, Wake Forest University, University of Oxford, University of Iceland, RIKEN, Medical University of Graz, Tulane University, Karolinska Institutet, University of Eastern Finland, University of Newcastle Australia, University of Cambridge, Fimlab (Finland), Inserm, Université de Lille, Institut Pasteur de Lille, Nagoya University, University Medical Center Groningen, University of Groningen, Institute of Genetics and Biophysics, Icahn School of Medicine at Mount Sinai, University of Alabama at Birmingham, IRCCS Materno Infantile Burlo Garofolo, University of Maryland, College Park, University Hospital Regensburg, Queen Mary University of London, University of Trieste, National University of Singapore, National University Health System, Boston University, University of Tartu, University of Lausanne, Tsinghua University, Universitätsmedizin Greifswald, Universität Greifswald, Massachusetts General Hospital, Monash University, Medical College of Wisconsin, Johns Hopkins University, Singapore National Eye Center, Singapore Eye Research Institute, Harbor–UCLA Medical Center, Centre Hospitalier Universitaire de Lille, University of Kelaniya, United States Department of Veterans Affairs, University of Wisconsin–Madison, University of North Carolina at Chapel Hill, The University of Texas Southwestern Medical Center, VA Tennessee Valley Healthcare System, University of Utah, Tampere University, University of Helsinki, Helsinki University Hospital, Finnish Institute for Health and Welfare, University of Split, Universidade de São Paulo, National Institute on Aging, National Institutes of Health, National Heart, Lung, and Blood Institute, Genome Institute of Singapore, GGZ inGeest, Amsterdam University Medical Centers, The University of Sydney, University of California, Irvine, University of Turku, Turku University Hospital, University of the Witwatersrand, Hunter Medical Research Institute, University of Copenhagen, University of Glasgow, Children's Hospital of Philadelphia, George Washington University, Centre Hospitalier Universitaire Vaudois, Huazhong University of Science and Technology, William Harvey Research Institute, Kurume University, The Lundquist Institute, Approches épidémiologiques et moléculaires intégratives visant à améliorer la compréhension des maladies chroniques liées au vieillissement, LabEx DISTALZ, Universidad Peruana Cayetano Heredia, Institut de Recherche en Sciences de la Santé, Clinical Research Unit Nanoro, Lifelines, Icelandic Heart Association, Jichi Medical University, National Center for Global Health and Medicine, University of Manchester, University of Illinois Chicago, University of Colorado Anschutz, University of Tampere, VA Boston Healthcare System, RIKEN Center for Integrative Medical Sciences, University of Southern California, New York University, University of Maryland, Baltimore, University of Maryland School of Medicine, Broad Institute
Language: English
Subfield: Genetics
Domain: Life Sciences
Open Access status: green
Awards: A Multi-Ethnic Study of Gene-Lifestyle Interactions in Cardiovascular Traits, A Multi-Ancestry Study of Gene-Lifestyle Interactions and Multi-Omics in Cardiometabolic Traits, G512016326, G8186663338, Infrastructure for mentored access to CHS data and specimens, Statistical Methods for Integrative Genomics in Cancer
OpenAlex ID: W7148668014