Abstract 6782: Discovery of a new class of mutant-targeted catalytic RAS(ON) inhibitors with retained antitumor activity in setting of emergent resistance due to elevated RAS flux
Year: 2026
Type: conference-abstract
Source: Cancer Research
Authors: Kyle Seamon, Jingwei Yin, Ouma Onguka, Oliver Lai, Cristina Blaj, Lingyan Jiang, Jinyu Liu, Yue Huang, Abby Marquez, John Knox, Jim Cregg, Yongxian Zhuang, Yu Chi Yang, Urszula N. Wasko, Qiang Liu, Jennifer A. Roth, Matthew G. Rees, Melissa Ronan, Benjamin J. Maldonato, Muhammad Ali Al-Radhawi, Kartika Jayashankar, Zhican Wang, Mike Flagella, Elsa Quintana, Elena S. Koltun, Mallika Singh, Zhengping Wang, Adrian L. Gill, David Wilds, Jingjing Jiang, Jacqueline A. Smith, Matthew Holderfield
Institutions: Revolution Medicines (United States), Broad Institute
Language: English
Subfield: Molecular Biology
Domain: Life Sciences
Open Access status: closed
OpenAlex ID: W7148687307
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