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Herpes zoster, antiviral therapy, and Alzheimer's disease: Turning association into an actionable prevention pathway

Year: 2026

Type: editorial

Abstract: Yang and Jiang synthesize evidence linking varicella-zoster virus exposure to Alzheimer's disease risk and lay out a clinically intuitive pathway from infection to intervention, spanning antiviral treatment and herpes zoster vaccination. The review is timely because it highlights potentially modifiable touchpoints in routine care for older adults. Building on their work, this commentary raises one pragmatic question: what additional evidence would most efficiently translate these associations into targeted, implementable prevention strategies-clarifying when risk is most actionable, which intervention features matter most, and which subgroups may benefit most?

Source: Journal of Alzheimer s Disease

DOI: 10.1177/13872877261438524

Authors: Jiuyuan Qin, Xue Xu, Yulin Zou

Institutions: Dalian Medical University, Second Affiliated Hospital of Dalian Medical University, Hubei University of Medicine, Universitätsmedizin Göttingen

Language: English

Topic: Herpesvirus Infections and Treatments

Subfield: Epidemiology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: green

OpenAlex ID: W7148687451

Cites: 9

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