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Abstract 7815: Efficacy of ABBV-706, a SEZ6-targeted topoisomerase 1 inhibitor ADC: A report from the Pediatric Preclinical In Vivo Testing (PIVOT) Program

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Year: 2026
Type: conference-abstract
Source: Cancer Research
DOI: 10.1158/1538-7445.am2026-7815
Authors: Elizabeth A. Stewart, Michael A. Dyer, Yael P. Mosse, John M. Maris, Xiao-Nan Li, Stefan Atkinson, Chen He, David N. Groff, Alvin Farrel, Yuchen Du, Jinnan Chen, Steven B. Neuhauser, Timothy M. Stearns, Emily L. Jocoy, Jee Young Kwon, Jeffrey H. Chuang, Emily Faivre, Kelly Doyle, Kimberly E. Ellison, Joshua F. Hernandez, Joann P. Palma, Michael Barnes, Pooja Hingorani, Nandini Rudra-Ganguly, Beverly A. Teicher, Carol J. Bult, Malcolm A. Smith
Institutions: St. Jude Children's Research Hospital, Children's Hospital of Philadelphia, Lurie Children's Hospital, Jackson Laboratory, The Jackson Laboratory for Genomic Medicine, AbbVie (United States), National Cancer Institute
Language: English

Topic: Cancer therapeutics and mechanisms
Subfield: Molecular Biology
Field: Biochemistry, Genetics and Molecular Biology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed
OpenAlex ID: W7148701272
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