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Abstract 5617: Humanized antibody Fab-TCR T cells targeting GPC2 effectively regress neuroblastoma via enhanced TCR signaling and sustained cytotoxicity

Year: 2026

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2026-5617

Authors: Mingyu Huo, Alex Quan, Dan Li, Laura E. Hutchins, Constanza Rodriguez, Jangsuk Oh, Hsi-En Tsao, Madeline Spetz, Elijah Edmondson, Dana Ashworth, Rui Zheng, Jing Zhou, Jinyun Chen, Jingbao Liu, Guangyan Xiong, Hongbing Zhang, Cheng Liu, Rosa Nguyen, Nan Li, Mitchell Ho

Institutions: National Institutes of Health, National Cancer Institute, Frederick National Laboratory for Cancer Research, Eureka Therapeutics (United States)

Language: English

Topic: CAR-T cell therapy research

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7148794825

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