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Abstract 512: Wild-type IDH1 inhibition induces homologous recombination deficiency and enhances PARP inhibitor sensitivity in pancreatic cancer.

Year: 2026

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2026-512

Authors: Mehrdad Zarei, Priyashree Sunita, Alexander Loftus, Faith Nakazzi, Semmer Ali, Om Prajapati, Soubhi Tahhan, Hallie J Graor, Shakti Prasad Pattanayak, Sami Abul-Khoudoud, Luke D. Rothermel, Rui Wang, Jonathan R. Brody, Jordan M. Winter

Institutions: Case Comprehensive Cancer Center, Case Western Reserve University, University Hospitals Cleveland Medical Center, Tulane University, University Hospitals of Cleveland, Oregon Health & Science University

Language: English

Topic: PARP inhibition in cancer therapy

Subfield: Oncology

Field: Medicine

Domain: Health Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7148804740

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