Work

Abstract 5743: Discovery of a novel orally available microtubule-destabilization agent that targets the colchicine binding site and exhibits antitumor activity in KRAS -mutant models

Year: 2026

Type: conference-abstract

Source: Cancer Research

DOI: 10.1158/1538-7445.am2026-5743

Authors: Yeni K. Romero, Joshua W. Large, Kylie Luther, Molly M. Hood, Ranjan Preet, Chase K. Crawley, Salim Javed, Yu Mi Ahn, Forrest A. Stanley, Bertrand Le Bourdonnec, Bryan D. Smith, Daniel L. Flynn, Jeffery D. Zwicker, Stacie L. Bulfer

Institution: Deciphera Pharmaceuticals (United States)

Language: English

Topic: Microtubule and mitosis dynamics

Subfield: Cell Biology

Field: Biochemistry, Genetics and Molecular Biology

Domain: Life Sciences

SDG: Good health and well-being

Open Access status: closed

OpenAlex ID: W7148811794

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