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Upstream ORFs control TNFR1 abundance and tissue tolerance to TNF

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Year: 2026
Type: article
Source: Science Immunology
DOI: 10.1126/sciimmunol.aeb6484
Authors: Biao Ma, Wenxin Lyu, John Rizk, Xiaoyue Han, Majken Kjær, Vinnycius Pereira Almeida, Malin Jessen, Max Benjamin Sauerland, Carol Sze Ki Leung, Benoit J. Van den Eynde, Xin Lu, Mads Gyrd-Hansen
Institutions: University of Copenhagen, University of Oxford, Ludwig Cancer Research, LEO Foundation, Ludwig Cancer Research, de Duve Institute, Walloon Excellence in Lifesciences and Biotechnology, UCLouvain
Language: English

Topic: Immune Response and Inflammation
Subfield: Immunology
Field: Immunology and Microbiology
Domain: Life Sciences
SDG: Good health and well-being

Open Access status: closed

Funders: Wellcome Trust, Cancer Research UK, Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung, Novo Nordisk Fonden, LEO Fondet
Awards: Identification of atypical ubiquitylation and its role in inflammatory signalling., G3209187204, G4129004604, G4539817374, Development of viral vectored vaccines for MAGE-expressing tumours, Regulation of Met1-linked ubiquitin and its impact on immune function
OpenAlex ID: W7148871485
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Cites: 57
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